Before downloading Illumina software, you must first read and agree to the following EULA.
Illumina discontinued support of the CentOS 7 operating system for all DRAGEN Servers on June 30, 2024. For information on upgrading DRAGEN servers to Oracle 8, refer to the DRAGEN secondary analysis Oracle 8 upgrade instructions available at https://knowledge.illumina.com.
For NextSeq 1000/2000 DRAGEN workflow installers, refer to the NextSeq 1000/2000 downloads page.
| DRAGEN Release | Installers | DRAGEN Software Release Notes | User Guide | Date Posted | Readme |
|---|---|---|---|---|---|
| v4.4 | v4.4.4 Software Release Notes | v4.4 User Guide | May 6, 2025 | ||
| v4.3 | v4.3.17 Software Release Notes | v4.3 User Guide | Jun 11, 2024 | DRAGEN v4.3 Readme | |
| v4.3.16 Software Release Notes | |||||
| v4.3.13 Software Release Notes | |||||
| v4.3.6 Software Release Notes | |||||
| v4.2 | v4.2.9 Software Release Notes | v4.2 User Guide | Apr 18, 2024 | DRAGEN v4.2 Readme | |
| v4.2.7 Software Release Notes | |||||
| v4.2.4 Software Release Notes | |||||
| v4.1 | v4.1.23 Software Release Notes | v4.1 User Guide | Mar 2, 2023 | DRAGEN v4.1 Readme | |
| v4.1.7 Software Release Notes | |||||
| DRAGEN v4.1.5 Software Release Notes | |||||
| v4.0 | DRAGEN v4.0.5 Software Release Notes | v4.0 User Guide | Dec 15, 2022 | DRAGEN v4.0 Readme | |
| DRAGEN v4.0.3 Software Release Notes |
| DRAGEN Release | Application | Description | Release Notes | Date Posted | User Guide | Date Posted | Readme |
|---|---|---|---|---|---|---|---|
| v4.4 | Heme WGS analysis-Windows | Download utility to enable secondary analysis of Heme WGS samples. Generates SNVs, INDELs, CNAs, SVs, FLT3-ITD, and DUX4 variants | Heme WGS Analysis Release Notes | May 28, 2025 | Heme WGS Analysis User Guide | May 9, 2025 | Readme |
| Heme WGS analysis-Unix | |||||||
| Heme WGS analysis-Mac | |||||||
| Solid WGS Tumor-Normal analysis-Windows | Download utility to enable secondary analysis of Solid WGS Tumor-Normal samples. Generates SNVs, INDELs, CNAs, SVs, TMB, MSI, HRD score, tumor purity, ploidy, and structural rearrangements. | Solid WGS Tumor-Normal Release Notes | May 28, 2025 | Solid WGS Tumor-Normal User Guide | May 9, 2025 | Readme | |
| Solid WGS Tumor-Normal analysis-Unix | |||||||
| Solid WGS Tumor-Normal analysis-Mac |
| DRAGEN Release | Installers | Date Posted | Software Release Notes | Date Posted | User Guide | Date Posted | EULA and Readme |
|---|---|---|---|---|---|---|---|
| v3.10.17 |
|
v3.10.17 Software Release Notes | May 9, 2024 | v3.10 User Guide | Apr 13, 2022 | v3.10 Software EULA and Readme | |
| v3.10.16 |
|
v3.10.16 Software Release Notes | Jan 16, 2024 | ||||
| v3.10.14 |
|
v3.10.14 Software Release Notes | May 6, 2024 | ||||
| v3.10.12 |
|
v3.10.12 Software Release Notes | Feb 6, 2023 | v3.10.12 Software EULA and Readme | |||
| v3.10.11 |
|
v3.10.11 Software Release Notes | Aug 8, 2023 | v3.10.11 Software EULA and Readme | |||
| v3.10.10 |
|
v3.10.10 Software Release Notes | Nov 1, 2022 | ||||
| v3.10.9 |
|
v3.10.9 Software Release Notes | Aug 4, 2022 | ||||
| v3.10.8 |
|
v3.10.8 Software Release Notes | April 12, 2022 | ||||
| v3.10.4 |
|
v3.10.4 Software Release Notes | Mar 9, 2022 | ||||
| v3.9.5 |
|
v3.9.5 Customer Release Notes | Aug 18, 2023 | v3.9 User Guide | Aug 2, 2021 | v3.9 Software EULA and Readme | |
| v3.9.3 |
|
v3.9.3 Software Release Notes | Aug 3, 2021 | ||||
| v3.8.9 |
|
v3.8.9 Software Release Notes | Jan 20, 2022 | v3.8 User Guide | Mar 26, 2021 | v3.8 Software EULA and Readme | |
| v3.8.4 |
|
v3.8.4 Software Release Notes | Mar 16. 2021 | ||||
| v3.7.5 |
|
v3.7.5 Software Release Notes | Oct 26, 2020 | ||||
| v3.6.6 |
|
v3.6.6 Software Release Notes | Jul 30, 2021 | v3.6 User Guide | Jun 22, 2020 | v3.6 Software EULA and Readme | |
| v3.6.4 |
|
v3.6.4 Software Release Notes | Jan 20, 2021 | ||||
| v3.6.3 |
|
v3.6.3 Software Release Notes | Jun 23, 2020 | ||||
| v3.4.5 |
|
v3.4.5 Software Release Notes | Aug 26, 2019 |